All scores were significantly higher in the deceased patients. The main precipitating factors of HE was infections predominantly spontaneous bacterial peritonitis ( n = 108, 54.0%) followed by variceal bleeding ( n = 39, 19.5%). Backward logistic regression analysis was used to identify the predictors of mortality. The receiver operating characteristic (ROC) curve was plotted, and the area under the ROC curve (AUROC) was calculated for each score. Demographic, clinical, and laboratory data as well as prognostic scores were compared in both deceased and improved groups. According to survival outcomes, patients were categorized into either improved or deceased.
APACHE II, CLIF-SOFA, MELD, MELD-Na, and CTP scores were calculated for all patients within the first 24 h after admission. Diagnosis and classification of HE were based on the West Haven criteria. Two hundred cirrhotic patients hospitalized with HE were included in the study. In the present study, we aimed to evaluate the prognostic value of these scores in patients with HE on a background of liver cirrhosis (type C). These scores were thoroughly investigated in HE associated with acute liver failure (type A). The most used scores are Child-Turcotte-Pugh (CTP), Model for End-stage Liver Disease (MELD), Chronic Liver Failure-Sequential Organ Failure Assessment (CLIF-SOFA), and Acute Physiology and Chronic Health Evaluation II (APACHE II). Many scoring systems are used to predict the outcome of HE in patients admitted to the intensive care unit (ICU). Hepatic encephalopathy (HE) is a serious condition associated with high rates of mortality.
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